Recombinant ITGAL (Efalizumab Biosimilar) 抗体
Quick Overview for Recombinant ITGAL (Efalizumab Biosimilar) 抗体 (ABIN7795106)
抗原
抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
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Expression System
- Mammalian cells
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原理
- Efalizumab Biosimilar, CD11a Monoclonal Antibody
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产品特性
- Efalizumab Biosimilar uses the same protein sequences as the therapeutic antibody efalizumab. Efalizumab is a monoclonal anti-CD11a antibody used to treat moderate to severe plaque psoriasis. Humanized IgG1 kappa isotype monoclonal antibody that binds to human CD11a. Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin. Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes. As a result efalizumab decreases cell surface expression of CD11a.
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纯化方法
- Protein A or G affinity column
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纯度
- >95 % by reducing SDS-PAGE
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内毒素水平
- < 1 EU per 1 mg of the protein by the LAL method
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免疫原
- Human CD11a
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anti-ITGAL (Efalizumab Biosimilar) antibody
适用: 人 FACS, BR 宿主: 兔 Chimeric hu1124 unconjugated Recombinant Antibody
anti-ITGAL (Efalizumab Biosimilar) antibody适用: 人 FACS, BR 宿主: Human Monoclonal hu1124 unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- > 3 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- ITGAL (Efalizumab Biosimilar)
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别名
- Efalizumab Biosimilar
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物质类
- Biosimilar
抗原
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